Benastatin B - CAS 138968-86-2

Benastatin B is a polyketide synthase-derived benastatin that has been found in Streptomyces and has diverse biological activities. It inhibits glutathione S-transferase (GST; Ki = 3.7 μM for the rat liver enzyme) .2 Benastatin B also inhibits the transglycosylase activity of A. baumannii, C. difficile, E. coli, and S. aureus recombinant penicillin-binding proteins (PBPs; IC50s = 16, 53.3, 30.7, and 31.6 μM, respectively) .3 It is active against several bacteria, including methicillin-resistant S. aureus (MRSA; MIC = 3.12 μg/ml) .

Others, GST, Antibacterial

Oxidation-Reduction, Others, Microbiology/Virology

138880

C30H30O7

502.55

OC1=C2C=3C(=C(O)C4=C(C3)C(C)(C)C=5C(C4=O)=C(O)C=C(O)C5)CCC2=CC(CCCCC)=C1C(O)=O

-20°C

Ice Packs

Small Compound