Bengamide B - CAS 104947-69-5

Potent inhibitor of NF-κB activation (IC50 = 85 nM) ; decreases IκBα phosphorylation. Attenuates LPS-induced nitric oxide production and expression of TNF-α, IL-6 and MCP. Suppresses proliferation of HeLa and HCT116 cells. Anti-inflammatory and antitumor.

NF-κB, Interleukin, Others

Others, NF-κB, Immunology/Inflammation

104873

C32H58N2O8

598.81

CCCCCCCCCCCCCC(=O)O[C@H]1CC[C@H](NC(=O)[C@H](OC)[C@H](O)[C@@H](O)[C@H](O)\C=C\C(C)C)C(=O)N(C)C1

-20°C

Ice Packs

Small Compound