Benzomalvin C - CAS 157047-98-8

Benzomalvin C is a weak antagonist of the neurokinin-1 (NK1) receptor, inhibiting binding of substance P by 46% at 100 μg/ml in vitro, and a weak inhibitor of indolamine 2,3-dioxygenase (IDO) with an IC50 value of 130 μM for recombinant IDO. Isolated from Penicillium, it contains an epoxide group at C-19 and C-20, absent in benzomalvins A, B, or E.

Others, Neurokinin receptor

Neuroscience, GPCR/G Protein, Others

156941

C24H17N3O3

395.418

CN1C(=O)c2ccccc2-n2c(nc3ccccc3c2=O)C11OC1c1ccccc1

-20°C

Ice Packs

Small Compound