BER-5 - CAS 724709-67-5

BER-5 is a potent MrgX2 antagonist, demonstrating broad-spectrum antagonistic activity against various MrgX2 agonists. It can inhibit Substance P (SP) -induced degranulation in LAD2 cells and alleviate SP-induced allergic reactions in mice. BER-5 is useful for researching mechanisms related to allergic reactions.

Calcium Channel, MRGPR, Interleukin

Immunology/Inflammation, Metabolism, Membrane transporter/Ion channel, GPCR/G Protein

724637

C20H16O4

320.34

O=C1OC=2C=C3OC=CC3=C(OCCCC=4C=CC=CC4)C2C=C1

-20°C

Ice Packs

Small Compound