Berubicin HCl - CAS 293736-67-1

Berubicin hydrochloride is the hydrochloride salt of the anthracycline derivative berubicin with potential antineoplastic activity. Berubicin intercalates into DNA and interrupts topoisomerase II activity, resulting in the inhibition of DNA replication and repair, and RNA and protein synthesis. Unlike other anthracycline derivatives, this agent crosses the blood-brain barrier (BBB) .

Apoptosis, Caspase, NF-κB, Others

Apoptosis, Others, Proteases/Proteasome, NF-κB

293668

C34H36ClNO11

670.1

OC=1C2=C([C@@H](O[C@H]3C[C@H](N)[C@H](OCC4=CC=CC=C4)[C@H](C)O3)C[C@@](C(CO)=O)(O)C2)C(O)=C5C1C(=O)C=6C(C5=O)=C(OC)C=CC6.Cl

-20°C

Ice Packs

Small Compound