Molfinity
Bestatin - CAS 58970-76-6
Bestatin - CAS 58970-76-6
SKU:MF-0017311-01
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Product Details
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Bioactivity
Bestatin (Ubenimex) competitively inhibits many aminopeptidases, including B, N and leucine aminopeptidases. Ubenimex is a microbial metabolite and dipeptide with potential immunomodulatory and antitumor activities. Aminopeptidases has been implicated in the process of cell adhesion and invasion of tumor cells. Therefore, inhibiting aminopeptidases may partially attribute to the antitumor effect of ubenimex. This agent also activates T lymphocyte, macrophage, and bone marrow stem cell as well as stimulates the release of interleukin-1 and -2, thus further enhances its antitumor activity.
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Target
LTR, Antibiotic, Antibacterial, Aminopeptidase
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Related Pathways
Metabolism, Immunology/Inflammation, Microbiology/Virology
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CAS Number
58888
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Purity
>99.99%
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Molecular Formula
C16H24N2O4
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Molecular Weight
308.37
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SMILES
C([C@H]([C@@H](C(N[C@@H](CC(C)C)C(O)=O)=O)O)N)C1=CC=CC=C1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Natural Product