BET-IN-16 - CAS 2089390-09-8

BET-IN-16 (Comp I), a bromodomain and extra-terminal (BET) inhibitor, demonstrates anticancer activity by impeding the growth of prostate cancer cells. It exhibits potent inhibitory effects with half-maximal inhibitory concentration (IC50) values of 0.043 μM for LNCaP cells and 0.034 μM for 22Rv1 cells [1].

Epigenetic Reader Domain

Chromatin/Epigenetic

2089390-09-8

C31H25N5O3

515.56

C(C)(N1C=2C(C(=C1)C3=CC=C(C(O)=O)C=C3)=NC=C(C2)C=4C(C)=NOC4C)(C5=CC=CC=N5)C6=CC=CC=N6

-20°C

Ice Packs

Small Compound