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BET-IN-20 - CAS 1300735-76-5

BET-IN-20 - CAS 1300735-76-5

MF-0147341-01

$2,156.00 USD
$2,156.00 USD
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Product Details

  • Bioactivity

    BET-IN-20 (compound 10), a BRD4 BD1 inhibitor (IC 50 =1.9 nM), exhibits significant anticancer properties. It promotes apoptosis in acute myeloid leukemia (AML) cells and arrests the cell cycle in the G0/G1 phase. Additionally, BET-IN-20 inhibits both c-Myc and CDK6, and enhances PARP cleavage [1].

  • Target

    Epigenetic Reader Domain, Apoptosis

  • Related Pathways

    Apoptosis, Chromatin/Epigenetic

  • CAS Number

    1300735-76-5

  • Molecular Formula

    C25H24N4O2

  • Molecular Weight

    412.48

  • SMILES

    [C@H](C)(N1C=2C=3C(=CC(=C(OC)C3)C=4C(C)=NOC4C)N=CC2N=C1C)C5=CC=CC=C5

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound