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Molfinity

BET-IN-21 - CAS 3014815-06-3

BET-IN-21 - CAS 3014815-06-3

MF-0116296-01

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Product Details

  • Bioactivity

    BET-IN-21 (compound 16) is a BET (Bromo and Extra-Terminal domain) inhibitor capable of penetrating the blood-brain barrier, with a Ki value of 230 nM. It suppresses microglial activation and demonstrates therapeutic effects in mice with experimental autoimmune encephalomyelitis.

  • Target

    Epigenetic Reader Domain

  • Related Pathways

    Chromatin/Epigenetic

  • CAS Number

    3014815-06-3

  • Molecular Formula

    C20H20N6

  • Molecular Weight

    344.41

  • SMILES

    N=1C=C(C=C(C1)C=2C(=NN(C2C)CC3CC3)C)C4=CC=NC=5N=CNC54

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound