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BET-IN-23 - CAS 2953287-57-3
BET-IN-23 - CAS 2953287-57-3
SKU:MF-0147342-01
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$2,682.50 USD
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Product Details
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Bioactivity
BET-IN-23 (Compound 23) is a BD2-selective BET inhibitor with an IC50 of 2.9 nM. It exhibits anticancer activity by significantly inhibiting the proliferation of acute myeloid leukemia (AML) cell lines, inducing G0/G1 arrest, and apoptosis in vitro [1].
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Target
Apoptosis, Epigenetic Reader Domain
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Related Pathways
Apoptosis, Chromatin/Epigenetic
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CAS Number
2953287-57-3
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Molecular Formula
C29H34FN3O5
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Molecular Weight
523.6
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SMILES
O(C1=C(C=C(C(C)(C)O)C=C1)C=2C(NCC(=O)N3CCOCC3)=CC(=O)N(C)C2)C4=C(C)C=C(F)C=C4C
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound