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Molfinity

BET-IN-27 - CAS 3054869-29-0

BET-IN-27 - CAS 3054869-29-0

MF-0110891-01

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Product Details

  • Bioactivity

    BET-IN-27 (compound 6C) is an orally active BET inhibitor with IC50 values of 3.3 nM (BRD4-BD2), 3.4 nM (BRD4-BD1), 4.1 nM (BRD2-BD1), 20.4 nM (BRD3-BD1), and 42.0 nM (BRDT-BD1) . It also exhibits antiproliferative activity.

  • Target

    Epigenetic Reader Domain, TGF-beta/Smad

  • Related Pathways

    Stem Cells, Chromatin/Epigenetic

  • CAS Number

    3054840

  • Molecular Formula

    C21H23N5O3S

  • Molecular Weight

    425.5

  • SMILES

    O=C1C=2NC=CC2C(=CN1C)C3=NC=4C=C(SC4C(=N3)N5CCOCC5)C(O)(C)C

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound