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Beta-Asarone - CAS 5273-86-9
Beta-Asarone - CAS 5273-86-9
SKU:MF-0013559-01
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Product Details
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Bioactivity
1. beta-Asarone (Cis-Isoelemicin) may be a potential preventive drug for Alzheimer's disease. 2. Beta-Asarone prevents autophagy and synaptic loss by reducing ROCK expression in SAMP8 mice. 3. The co-administration of beta-Asarone (Cis-Isoasarone) and l-dopa may contribute to the treatment of 6-OHDA-induced damage in rats by inhibiting autophagy activity. 4. Beta-Asarone exhibits anti-inflammatory effects by suppressing the production of pro-inflammatory mediators through NF-κB signaling and the JNK pathways in activated microglial cells and might be developed as a promising candidate to treat various neuroinflammatory diseases.
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Target
JNK, NF-κB
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Related Pathways
NF-κB, MAPK
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CAS Number
5178
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Purity
0.9997
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Molecular Formula
C12H16O3
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Molecular Weight
208.25
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SMILES
COc1cc(OC)c(\C=C/C)cc1OC
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Natural Product