Beta-Hydroxyisovalerylshikonin - CAS 7415-78-3

Beta-Hydroxyisovalerylshikonin is an inhibitor of protein-tyrosine kinases such as v-Src and EGFR, and has been shown to induce apoptosis in several human tumor cell lines. Beta-Hydroxyisovalerylshikonin significantly decreased viability of HCT116 cells (IC50 values = 30.9 μg/mL) .

Prostaglandin Receptor, Fatty Acid Synthase, AMPK, EGFR, Src, Tyrosine Kinases

Immunology/Inflammation, PI3K/Akt/mTOR signaling, Angiogenesis, Tyrosine Kinase/Adaptors, Chromatin/Epigenetic, Metabolism, JAK/STAT signaling, GPCR/G Protein

7415-78-3

0.9959

C21H24O7

388.41

CC(C)=CC[C@@H](OC(=O)CC(C)(C)O)C1=CC(=O)c2c(O)ccc(O)c2C1=O

-20°C

Ice Packs

Natural Product