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Bexotegrast - CAS 2376257-44-0
Bexotegrast - CAS 2376257-44-0
SKU:MF-0013583-01
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$57.84 USD
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$57.84 USD
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Product Details
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Bioactivity
Bexotegrast (PLN-74809) is an orally active and potent inhibitor of αvβ6 and αvβ1 integrins with antifibrotic effects, inhibiting αvβ6 and αvβ1-induced activation of TGF-β. It is applicable for studies of idiopathic pulmonary fibrosis (IPF) and non-specific interstitial pneumonia (NSIP) .
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Target
Integrin
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Related Pathways
Cytoskeletal Signaling
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CAS Number
2376213
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Purity
0.9953
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Molecular Formula
C27H36N6O3
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Molecular Weight
492.61
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SMILES
N([C@@H](CCN(CCCCC=1NC=2C(=CC1)CCCN2)CCOC)C(O)=O)C=3C4=C(N=CN3)C=CC=C4
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound