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Molfinity

Bexotegrast - CAS 2376257-44-0

Bexotegrast - CAS 2376257-44-0

SKU:MF-0013583-01

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  • Bioactivity

    Bexotegrast (PLN-74809) is an orally active and potent inhibitor of αvβ6 and αvβ1 integrins with antifibrotic effects, inhibiting αvβ6 and αvβ1-induced activation of TGF-β. It is applicable for studies of idiopathic pulmonary fibrosis (IPF) and non-specific interstitial pneumonia (NSIP) .

  • Target

    Integrin

  • Related Pathways

    Cytoskeletal Signaling

  • CAS Number

    2376213

  • Purity

    0.9953

  • Molecular Formula

    C27H36N6O3

  • Molecular Weight

    492.61

  • SMILES

    N([C@@H](CCN(CCCCC=1NC=2C(=CC1)CCCN2)CCOC)C(O)=O)C=3C4=C(N=CN3)C=CC=C4

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound