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BI-2545 - CAS 2162961-71-7
BI-2545 - CAS 2162961-71-7
SKU:MF-0032275-01
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Product Details
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Bioactivity
BI-2545 is a potent and selective autotaxin (ATX) inhibitor with IC50 values of 2.2 nM and 3.4 nM for human and rat ATX, respectively, and reduces plasma LPA levels in rats.
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Target
PDE
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Related Pathways
Metabolism
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CAS Number
2162883
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Molecular Formula
C23H19F6N5O3
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Molecular Weight
527.42
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SMILES
C(NC(=O)C=1C=C2C(=CC1)N=NN2)[C@@H]3[C@@]4([C@]3(CN(C(OCC5=CC(C(F)(F)F)=CC(C(F)(F)F)=C5)=O)C4)[H])[H]
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound