BI-4732 - CAS 2769715-68-4

BI-4732 is an epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) with high blood-brain barrier permeability, antitumor activity, inhibition of EGFR activation, and inhibition of T790M mutations.

Akt, EGFR, ERK, S6 Kinase

PI3K/Akt/mTOR signaling, Angiogenesis, Tyrosine Kinase/Adaptors, JAK/STAT signaling, Cytoskeletal Signaling, MAPK

2769715-68-4

0.9888

C32H36N10O2

592.69

CN1C=2C(=C(N=C(C2)N3C=4C(C=N3)=C(C)N=C(C4)C=5C(OC)=CC=NC5)N6[C@@]7(C[C@](C6)(OC7)[H])[H])N=C1N8C[C@@]9(N(CC8)CCC9)[H]

-20°C

Ice Packs

Small Compound