BI-4834 - CAS 876371-13-0

BI-4834 is a potent and selective Polo-like kinase 1 (PLK1) inhibitor. BI-4834 is also analogue (or Me-Too) of BI-2536. In vitro test shows that BI 4834 inhibits PLK1 with IC50=7.6 nm, but with higher selectivity over the related enzyme PLK3 (IC50 198.4 nm) as BI-2536.

Others

Others

876358

C32H47N7O4

593.76

C(C)(C)N1C=2C(N(C)C(=O)[C@H]1CC)=CN=C(NC3=C(OC)C=C(C(N[C@@H]4CC[C@H](CC4)N5C[C@@H](C)O[C@@H](C)C5)=O)C=C3)N2

-20°C

Ice Packs

Small Compound