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Molfinity

BI-671800 - CAS 1093108-50-9

BI-671800 - CAS 1093108-50-9

MF-0006288-01

$49.62 USD
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Product Details

  • Bioactivity

    BI-671800 (AP-761) is a highly specific and potent antagonist of chemoattractant receptor-homologous molecule on Th2 cells (DP2/CRTH2) . With IC50 values of 4.5 nM and 3.7 nM for PGD2 binding to CRTH2 in hCRTH2 and mCRTH2 transfected cells, respectively. BI-671800 has the potential to treat poorly controlled asthma[2].

  • Target

    Prostaglandin Receptor, GPCR

  • Related Pathways

    Immunology/Inflammation, Endocrinology/Hormones, GPCR/G Protein

  • CAS Number

    1093108-50-9

  • Purity

    0.9919

  • Molecular Formula

    C25H26F3N5O3

  • Molecular Weight

    501.5

  • SMILES

    CN(C)c1nc(Cc2ccc(NC(=O)c3ccc(cc3)C(F)(F)F)cc2)nc(N(C)C)c1CC(O)=O

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound