BI8622 - CAS 1875036-74-0

BI8622 is a ubiquitin ligase HUWE1-specific antagonist that restores the level of RP2 mutants in retinal cell lines and inhibits the activation of NLRP3, NLRC4, and AIM2 inflammatory vesicles in cells.

DNA/RNA Synthesis, E1/E2/E3 Enzyme, c-Myc

Ubiquitination, Cell Cycle/Checkpoint, DNA Damage/DNA Repair

1874962

0.9828

C25H26N6O

426.51

N#CC1(C=2C=CC=CC2)CCN(C=3N=CN=C(C(=O)NC4=CC=C(C=C4)CN)C3C)CC1

-20°C

Ice Packs

Small Compound