(-) BI97D6 - CAS 1430067-36-9

(-) BI97D6 is a broad-spectrum inhibitor of the Bcl-2 protein family, exhibiting inhibitory effects on Mcl-1, Bcl-2, Bcl-xL, and Bcl-w, with IC50 values of 0.025, 0.031, 0.076, and 0.122 μM respectively. This compound stimulates cell death through the mitochondrial apoptosis pathway mediated by Bak and Bax. Additionally, (-) BI97D6s inhibition of Mcl-1 effectively induces apoptosis in acute myeloid leukemia (AML) cells.

1430067-36-9

C36H26O8

586.59

O=C1C2=CC(O)=C(O)C(=C2C(=O)C(=C1C=3C(=O)C4=CC(O)=C(O)C(=C4C(=O)C3C)CC=5C=CC=CC5)C)CC=6C=CC=CC6

-20°C

Ice Packs

Small Compound