Bicuculline methochloride - CAS 38641-83-7

Bicuculline methochloride is a competitive GABAA receptor antagonist and allosteric inhibitor with an IC50 of 1.7 μM. It blocks Ca2+-dependent activation of potassium channels, exhibits convulsant activity, and is suitable for epilepsy research.

GABA Receptor

Membrane transporter/Ion channel, Neuroscience

38551

0.9935

C21H20ClNO6

417.84

C[N+]1(C)[C@]([C@]2(C3=C(C(=O)O2)C4=C(C=C3)OCO4)[H])(C5=C(C=C6C(=C5)OCO6)CC1)[H].[Cl-]

-20°C

Ice Packs

Small Compound