Bigelovin - CAS 3668-14-2

Bigelovin is a selective retinoid X receptor α agonist. Bigelovin suppresses tumor growth through inducing apoptosis and autophagy via the inhibition of mTOR pathway regulated by ROS generation.It is also known as a potent cytotoxic sesquiterpene lactone from Inula sp.

ROS, Autophagy, Retinoid Receptor, Apoptosis, RAR/RXR, Reactive Oxygen Species

Immunology/Inflammation, Metabolism, Apoptosis, Autophagy, NF-κB

3652

0.9972

C17H20O5

304.34

[H][C@]12C[C@@H](C)[C@]3([H])C=CC(=O)[C@@]3(C)[C@@H](OC(C)=O)[C@@H]1C(=C)C(=O)O2

-20°C

Ice Packs

Natural Product