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BIHC - CAS 1642826-40-1
BIHC - CAS 1642826-40-1
SKU:MF-0113305-01
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Product Details
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Bioactivity
BIHC is a Her2-CD3 bispecific antibody, constructed from an anti-Her2 single-domain antibody and an anti-CD3 single-chain variable fragment (Fv) in an IgG-like format. BIHC demonstrates effective in vivo antitumor activity, specifically binding to Her2-expressing tumor cells and efficiently killing Her2-positive cancer cells by recruiting T cells, thus serving as a research tool for Her2-positive cancers.
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Target
EGFR, Integrin
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Related Pathways
JAK/STAT signaling, Angiogenesis, Tyrosine Kinase/Adaptors, Cytoskeletal Signaling
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CAS Number
1642785
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Molecular Formula
C26H21ClN2O6
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Molecular Weight
492.908
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SMILES
O=C1OC=2C=CC=CC2C(O)=C1C(C=3NC(=NC3Cl)CCCC)C=4C(=O)OC=5C=CC=CC5C4O
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound