Biotinylated-JQ1 - CAS 1635437-52-3

Biotinylated-JQ1 (Biotin-JQ1), a biotinylated derivative of JQ1, selectively binds to the BRD4 bromodomain with high affinity. It effectively inhibits the proliferation of MM1.S multiple myeloma cells, demonstrating an EC50 of 0.4 μM [1].

Others, Epigenetic Reader Domain

Chromatin/Epigenetic, Others

1635382

C39H53ClN8O6S2

829.47

CC=1C2=C(N3C([C@H](CC(NCCCOCCOCCOCCCNC(CCCC[C@H]4[C@@]5([C@](CS4)(NC(=O)N5)[H])[H])=O)=O)N=C2C6=CC=C(Cl)C=C6)=NN=C3C)SC1C

-20°C

Ice Packs

Small Compound