Bis (maltolato) oxovanadium (IV) - CAS 38213-69-3

Bis (maltolato) oxovanadium (IV) (BMOV) is a potent, reversible, competitive, and orally active pan-PTP (protein tyrosine phosphatases) inhibitor with insulin-mimicking effects and anti-diabetic properties. BMOV is a potent insulin sensitizer and has been shown to improve cardiac dysfunctions in diabetic models. BMOV inhibits HCPTPA, PTP1B, HPTPβ, and SHP2 with IC50s of 126 nM, 109 nM, 26 nM, and 201 nM, respectively [1][2].

Phosphatase

Metabolism

38141

0.99918

C12H10O7V

317.15

O=[V+2]12([O-]C=3C(=O1)C=COC3C)[O-]C=4C(=O2)C=COC4C

-20°C

Ice Packs

Small Compound