Bisindolylmaleimide VIII - CAS 125313-65-7

Bisindolylmaleimide VIII (Ro-31-7549) is a selective and potent protein kinase C (PKC) inhibitor with good inhibition of PKC-α, PKC-β I, PKC-β II, PKC-γ, and PKC-ε.Bisindolylmaleimide VIII Bisindolylmaleimide VIII inhibits T cell-mediated autoimmune diseases and enhances Fas-mediated apoptosis through a protein kinase C-independent mechanism.

PKC, Apoptosis

Apoptosis, Cytoskeletal Signaling, Chromatin/Epigenetic

125241

0.9801

C24H22N4O2

398.46

O=C1NC(=O)C(C2=CN(C=3C=CC=CC23)CCCN)=C1C4=CN(C=5C=CC=CC45)C

-20°C

Ice Packs

Small Compound