Bisindolylmaleimide VIII acetate - CAS 138516-31-1

Bisindolylmaleimide VIII acetate (Ro 31-7549 acetate) is a potent and selective PKC inhibitor (IC50: 158 nM for rat brain PKC) with IC50 values of 53, 195, 163, 213, and 175 nM for PKC-α, PKC-βI, PKC-βII, PKC-γ, and PKC-ε, respectively.

PKC, Apoptosis

Cytoskeletal Signaling, Chromatin/Epigenetic, Apoptosis

138484

0.9927

C26H26N4O4

458.51

CC(O)=O.Cn1cc(C2=C(C(=O)NC2=O)c2cn(CCCN)c3ccccc23)c2ccccc12

-20°C

Ice Packs

Small Compound