BJP-07-017-3 - CAS 2468783-22-2

BJP-07-017-3 is an inhibitor of proline cis-trans isomerase (Pin1) with an IC50 of 9 nM. It forms a covalent bond with Cys113 of Pin1, inducing conformational changes that decrease its stability and lead to proteasome-dependent degradation.

Others

Others

2468759

C35H45ClN8O6

709.235

C([C@H](NC(=O)[C@H]1N(C([C@H](CC2=CC=CC=C2)N(C(CCl)=O)C)=O)CCCC1)C(N[C@@H](CCCNC(N)=O)C(N)=O)=O)C=3C=4C(NC3)=CC=CC4

-20°C

Ice Packs

Small Compound