BKN-1 - CAS 1607831-82-2

BKN-1, a bifunctional ligand, facilitates the tracking of mtG4s (G-quadruplexes, four-stranded DNA structures containing Hoogsteen bonds) formation via far-red emission and can induce mitochondrial dysfunction. This compound exhibits anti-tumor properties, potentially causing mtDNA loss, damaging mitochondrial integrity, reducing ATP levels, and triggering ROS imbalance, which can lead to apoptosis and autophagy [1].

Apoptosis, Autophagy

Apoptosis, Autophagy

1607831-82-2

C31H29IN2

556.48

CC1(C)C2=C([N+](C)=C1C=CC=3C=C4C(=CC3)N(CC)C=5C4=CC=CC5)C=CC=6C2=CC=CC6.[I-]

-20°C

Ice Packs

Small Compound