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BKT-300 - CAS 2551033-16-8
BKT-300 - CAS 2551033-16-8
SKU:MF-0115583-01
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Product Details
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Bioactivity
BKT-300 is a potent and selective inhibitor of Protein regulator of cytokinesis 1 (PRC1), with a Kd value of 28.3 nM. It disrupts microtubule architecture, induces G2/M phase arrest, mitotic catastrophe, and caspase-3-dependent apoptosis, presenting potential as a novel therapy for advanced acute myeloid leukemia (AML) .
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Target
Others
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Related Pathways
Others
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CAS Number
2551009
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Molecular Formula
C22H25NO6
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Molecular Weight
399.44
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SMILES
O=C1NC=2C(OC3=CC=C(O)C=C3OC)=CC(OC)=CC2C(O)=C1CCCCC
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound