Bleximenib oxalate - CAS 2866179-95-3

Bleximenib oxalate (Menin-MLL inhibitor 24 oxalate) is a selective and highly efficient menin-MLL inhibitor. It shows antiproliferative activity in acute lymphoblastic leukemia (ALL) cell lines and inhibits the binding of the menin-KMT2A complex to chromatin at the target gene promoter.

Epigenetic Reader Domain, Histone Methyltransferase, Apoptosis, FLT

Angiogenesis, Tyrosine Kinase/Adaptors, Chromatin/Epigenetic, Apoptosis

2866081

C34H52FN7O7

689.82

C(C(O)=O)(O)=O.[C@@H](CCCN(CCOC)C)(C(C)C)N1CC2(CN(CC2)C=3C(OC4=C(C(N(C(C)C)CC)=O)C=C(F)C=C4)=NN=CN3)C1

-20°C

Ice Packs

Small Compound