Blixeprodil - CAS 2881017-49-6

Blixeprodil (GM-1020) is an orally active NMDA receptor antagonist with an affinity of Ki = 3.25 μM in rat cortical tissue. It inhibits NR1/2A-NMDAR-mediated currents in HEK293 cells with an IC50 of 1.192 μM. Blixeprodil demonstrates antidepressant effects in rat models and exhibits blood-brain barrier permeability.

IGluR

Neuroscience, Membrane transporter/Ion channel

2880962

C13H16FNO

221.271

N(C)[C@@]1(C(=O)CCCC1)C2=CC=C(F)C=C2

-20°C

Ice Packs

Small Compound