BLK-IN-2 - CAS 2694871-86-6

BLK-IN-2 is a potent, selective, and irreversible inhibitor of B-Lymphoid tyrosine kinase (BLK), demonstrating significant efficacy with an IC50 of 5.9 nM. Additionally, it exhibits an inhibitory effect on BTK (Bruton's tyrosine kinase) with an IC50 of 202.0 nM. This compound has shown strong antiproliferative activities against various lymphoma cells.

Others, BTK

Tyrosine Kinase/Adaptors, Angiogenesis, Others

2694779

C39H41N9O3

683.8

C(NC1=CC(C(NC=2C=NC(NC3=CC(NC4CCN(C(C=CCN(C)C)=O)CC4)=CC=C3)=NC2)=O)=C(C)C=C1)(=O)C5=CC6=C(C=C5)C=NC=C6

-20°C

Ice Packs

Small Compound