BLT2 antagonist-1 - CAS 2069220-61-5

BLT2 antagonist-1 (compound 15b) is a selective inhibitor of the BLT2 receptor, impeding the chemotaxis of CHO-BLT2 cells at an IC50 of 224 nM without affecting CHO-BLT1 cell chemotaxis. It blocks the interaction between LTB4 and the BLT2 receptor with a K_i of 132 nM and may serve as a research tool for inflammatory airway diseases, including asthma and chronic obstructive pulmonary disease [1].

Leukotriene Receptor

GPCR/G Protein

2069154

C26H26FNO4

435.49

N(CC1=CC=C(C=C1)C2=CC=C(OCC(O)=O)C=C2)(C(CCCC)=O)C3=CC(F)=CC=C3

-20°C

Ice Packs

Small Compound