BMS-1 - CAS 1675201-83-8

BMS-1 (PD-1/PD-L1 inhibitor 1) is an inhibitor of the PD1-PD-L1 protein-protein interaction. It also acts as an immunomodulator. Programmed death ligand 1 (PD-L1) is a protein in humans that is encoded by the CD274 gene and the upregulation of PD-L1 allows Ys to evade the host immune system. High tumor expression of PD-L1 was associated with increased tumor aggressiveness and a 4.5-fold increased risk of death.

PD-1/PD-L1, Apoptosis

Cell Cycle/Checkpoint, Apoptosis, Immunology/Inflammation

1675110

0.9986

C29H33NO5

475.58

COc1cc(OCc2cccc(c2C)-c2ccccc2)cc(OC)c1CN1CCCC[C@H]1C(O)=O

-20°C

Ice Packs

Small Compound