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BMS-1166 hydrochloride - CAS 2113650-05-6
BMS-1166 hydrochloride - CAS 2113650-05-6
SKU:MF-0032373-01
Regular price
$245.68 USD
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Sale price
$245.68 USD
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Product Details
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Bioactivity
Motixafortide (BKT140 4-fluorobenzoyl) is an antagonist of CXCR4 (IC50: 1 nM) . BMS-1166 hydrochloride is an inhibitor of PD-1/PD-L1 interaction (IC50: 1.4 nM) . BMS-1166 rivalries the inhibitory effect of PD-1/PD-L1 immune checkpoint on T cell activation.
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Target
PD-1/PD-L1, Others
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Related Pathways
Apoptosis, Immunology/Inflammation, Others, Cell Cycle/Checkpoint
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CAS Number
2113650-05-6
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Molecular Formula
C36H34Cl2N2O7
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Molecular Weight
677.57
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SMILES
Cl.Cc1c(COc2cc(OCc3cccc(c3)C#N)c(CN3C[C@H](O)C[C@@H]3C(O)=O)cc2Cl)cccc1-c1ccc2OCCOc2c1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound