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Molfinity

BMS-1166 hydrochloride - CAS 2113650-05-6

BMS-1166 hydrochloride - CAS 2113650-05-6

SKU:MF-0032373-01

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  • Bioactivity

    Motixafortide (BKT140 4-fluorobenzoyl) is an antagonist of CXCR4 (IC50: 1 nM) . BMS-1166 hydrochloride is an inhibitor of PD-1/PD-L1 interaction (IC50: 1.4 nM) . BMS-1166 rivalries the inhibitory effect of PD-1/PD-L1 immune checkpoint on T cell activation.

  • Target

    PD-1/PD-L1, Others

  • Related Pathways

    Apoptosis, Immunology/Inflammation, Others, Cell Cycle/Checkpoint

  • CAS Number

    2113650-05-6

  • Molecular Formula

    C36H34Cl2N2O7

  • Molecular Weight

    677.57

  • SMILES

    Cl.Cc1c(COc2cc(OCc3cccc(c3)C#N)c(CN3C[C@H](O)C[C@@H]3C(O)=O)cc2Cl)cccc1-c1ccc2OCCOc2c1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound