BMS-1233 - CAS 2447065-99-6

BMS-1233 is an orally effective programmed death ligand 1 (PD-L1) inhibitor with an IC50 of 14.5 nM. This compound promotes the death of HepG2 cells in a co-culture model with Jurkat T cells and exhibits antitumor activity against melanoma in mouse models.

PD-1/PD-L1

Immunology/Inflammation, Apoptosis, Cell Cycle/Checkpoint

2447065-99-6

C35H33ClN2O4

581.1

N#CC1=CC=CC(=C1)COC2=CC(OCC3=CC=CC(C=4C=CC=CC4)=C3C)=C(Cl)C=C2CN5CCCCC5C(=O)O

-20°C

Ice Packs

Small Compound