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BMS 299897 - CAS 290315-45-6

BMS 299897 - CAS 290315-45-6

MF-0000863-01

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Product Details

  • Bioactivity

    BMS 299897 is a sulfonamide γ-secretase inhibitor with an IC50 of 7 nM for inhibiting Aβ production in HEK293 cells stably overexpressing amyloid precursor protein (APP) .

  • Target

    Gamma-secretase, Beta Amyloid

  • Related Pathways

    Neuroscience, Proteases/Proteasome, Stem Cells

  • CAS Number

    290315-45-6

  • Purity

    >99.99%

  • Molecular Formula

    C24H21ClF3NO4S

  • Molecular Weight

    511.94

  • SMILES

    C[C@@H](N(c1cc(F)ccc1F)S(=O)(=O)c1ccc(Cl)cc1)c1ccc(F)cc1CCCC(O)=O

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound