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BMS 599626 2HCl - CAS 1781932-33-9

BMS 599626 2HCl - CAS 1781932-33-9

MF-0006287-01

$47.38 USD
$32.50 USD $47.38 USD
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Product Details

  • Bioactivity

    BMS 599626 2HCl (873837-23-1 (HCl) ) (AC480 dihydrochloride) is a selective inhibitor of HER1 and HER2 (IC50s: 20 nM and 30 nM), ~8-fold less potent to HER4, >100-fold to Lck, VEGFR2, c-Kit, MET, etc.

  • Target

    HER

  • Related Pathways

    Angiogenesis, Tyrosine Kinase/Adaptors, JAK/STAT signaling

  • CAS Number

    1781932-33-9

  • Purity

    0.9994

  • Molecular Formula

    C27H29FN8O3Cl2

  • Molecular Weight

    603.48

  • SMILES

    O=C(OC[C@@H]1COCCN1)NC2=CN3C(C(NC4=CC=C(N(N=C5)CC6=CC(F)=CC=C6)C5=C4)=NC=N3)=C2C.Cl.Cl

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound