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BMS-599626 Hydrochloride - CAS 873837-23-1

BMS-599626 Hydrochloride - CAS 873837-23-1

MF-0013192-01

$37.66 USD
$37.66 USD
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Product Details

  • Bioactivity

    BMS-599626 Hydrochloride (AC480 Hydrochloride) is an orally bioavailable inhibitor of the HER1, HER2, and HER4 tyrosine kinases (IC50 = 22, 32, and 190 nM, respectively) with potential antineoplastic activity, inhibiting the proliferation of tumor cells that overexpress these receptors.

  • Target

    EGFR, HER

  • Related Pathways

    JAK/STAT signaling, Angiogenesis, Tyrosine Kinase/Adaptors

  • CAS Number

    873813

  • Purity

    >99.99%

  • Molecular Formula

    C27H28ClFN8O3

  • Molecular Weight

    567.01

  • SMILES

    Cl.Cc1c(NC(=O)OC[C@@H]2COCCN2)cn2ncnc(Nc3ccc4n(Cc5cccc(F)c5)ncc4c3)c12

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound