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Molfinity
BMS-737 - CAS 1356053-63-8
BMS-737 - CAS 1356053-63-8
SKU:MF-0121774-01
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Product Details
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Bioactivity
BMS-737 (compound 33), a non-steroidal, reversible small molecule inhibitor, demonstrates 11-fold selectivity for CYP17 lyase over CYP17 hydroxylase. This compound is engineered to target castration-resistant prostate cancer (CRPC) and effectively lowers testosterone levels, while maintaining stable orrodermal hormone and glucocorticoid levels.
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Target
Cytochromes P450
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Related Pathways
Metabolism
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CAS Number
1356053-63-8
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Molecular Formula
C16H11FN6
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Molecular Weight
306.3
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SMILES
FC1=CC=C(C=C1)N2N=CC=3C2=NC=CC3C=4C=NC=NC4N
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound