BMS-751324 - CAS 948842-66-8

BMS-751324, a p38α MAPK inhibitor, features a carbamyl-methyl linkage precursor with esters and phosphate functional groups from hydroxyphenylacetic acid (HPA) . It effectively reduces foot swelling and suppresses LPS-induced TNFα production in an arthritic rat model.

P38 MAPK, Others, TNF

Apoptosis, MAPK, Others

948768

C32H35N6O10P

694.63

N(C=1C=2N(C=C(C(N(C(OCOC(CC3=CC=C(OP(=O)(O)O)C=C3)=O)=O)CCC)=O)C2C)N=CN1)C4=CC(C(NC5CC5)=O)=CC=C4C

-20°C

Ice Packs

Small Compound