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BMS-911543 - CAS 1271022-90-2
BMS-911543 - CAS 1271022-90-2
SKU:MF-0019019-01
Regular price
$48.12 USD
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$48.12 USD
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Product Details
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Bioactivity
BMS-911543 is a potent and selective inhibitor of JAK2 with IC50 of 1.1 nM, ~350-, 75- and 65-fold selective to JAK1, JAK3 and TYK2, respectively. Phase 1/2.
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Target
Tyrosine Kinases, JAK, Histone Methyltransferase
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Related Pathways
Tyrosine Kinase/Adaptors, Chromatin/Epigenetic, JAK/STAT signaling, Angiogenesis, Stem Cells
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CAS Number
1270930
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Purity
0.9998
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Molecular Formula
C23H28N8O
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Molecular Weight
432.52
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SMILES
CCn1c(cc2c1nc(Nc1cc(C)n(C)n1)c1ncn(C)c21)C(=O)N(C1CC1)C1CC1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound