BMS-986143 - CAS 1643372-95-5

BMS-986143, an orally active, reversible BTK inhibitor with an IC50 value of 0.26 nM, is designed for autoimmune disease research. Additionally, it targets TEC, BLK, BMX, TXK, FGR, YES1, and ITK, exhibiting IC50s of 3 nM, 5 nM, 7 nM, 10 nM, 15 nM, 19 nM, and 21 nM, respectively [1].

Others, BTK

Tyrosine Kinase/Adaptors, Angiogenesis, Others

1643272

C31H24Cl2N4O4

587.45

ClC=1C(=C2C(=C(C(N)=O)C1)NC=3C2=CC=C(C(C)(C)O)C3)C4=C(C)C(=CC=C4)N5C(=O)N6C(=CC5=O)C(Cl)=CC=C6

-20°C

Ice Packs

Small Compound