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BMS-986163 - CAS 1801151-09-6
BMS-986163 - CAS 1801151-09-6
SKU:MF-0032382-01
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Product Details
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Bioactivity
BMS-986163 is an effective GluN2B negative allosteric modulator prodrug that converts to the active form BMS-986169 (Ki=4 nM, IC50=24 nM) in vivo, exhibiting antidepressant-like activity in mice.
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Target
NMDAR
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Related Pathways
Neuroscience
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CAS Number
1801151-09-6
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Molecular Formula
C23H28FN2O5P
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Molecular Weight
462.45
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SMILES
O=C1[C@@H](CCN1CC2=CC=C(C)C=C2)N3C[C@@H](F)[C@@H](CC3)C4=CC=C(OP(=O)(O)O)C=C4
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound