BMS-986189 - CAS 1629665-96-8

BMS-986189, a macrocyclic peptide inhibitor of PD-L1 (IC 50: 1.03 nM), can be utilized for cancer research [1].

PD-1/PD-L1

Immunology/Inflammation, Cell Cycle/Checkpoint, Apoptosis

1629665-96-8

C91H131N21O21S

1887.21

C(C=1C=2C(N(CC(O)=O)C1)=CC=CC2)[C@H]3C(=O)N(C)[C@@H](CCCC)C(=O)N(C)[C@@H](CCCC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(NCC(N)=O)=O)CSCC(=O)N[C@@H](CC4=CC=C(O)C=C4)C(=O)N(C)[C@@H](C)C(=O)N[C@@H](CC(N)=O)C(=O)N5[C@](C(=O)N[C@@H](CN)C(=O)N[C@@H](CC(C)C)C(=O)N6[C@](C(=O)N[C@@H](CC=7C=8C(NC7)=CC=CC8)C(=O)N[C@@H](CCN)C(=O)N3)(C[C@@H](O)C6)[H])(CCC5)[H]

-20°C

Ice Packs

Peptide