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Molfinity

BMS-986397 - CAS 2564486-44-6

BMS-986397 - CAS 2564486-44-6

MF-0122674-01

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Product Details

  • Bioactivity

    BMS-986397 is a casein kinase 1 α molecular gel degrading agent based on cereblon, which can promote rapid apoptosis and cell cycle arrest of TP53 wild-type acute myeloid leukemia cells.

  • Target

    Ligand for E3 Ligase, Casein Kinase, Molecular Glues

  • Related Pathways

    PROTAC, Metabolism, Stem Cells

  • CAS Number

    2564486-44-6

  • Molecular Formula

    C21H16ClF3N4O4

  • Molecular Weight

    480.82

  • SMILES

    O=C1N(CC=2C1=CC=C(C(N[C@@H]([C@@](F)(F)F)C3=C(Cl)C=CC=N3)=O)C2)[C@@H]4C(=O)NC(=O)CC4

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    PROTAC