BMS-986463 - CAS 3025467-07-3

BMS-986463 is a WEE1 kinase molecule gel degrader and a CRBN E3 ligase regulator (CELMoD) . BMS-986463 significantly inhibits tumor regression and reduces the level of phosphorylated CDK2. BMS-986463 can be used in the research of advanced malignant solid tumors such as non-small cell lung cancer (NSCLC) .

Molecular Glues, Wee1

PROTAC, Cell Cycle/Checkpoint

3025467-07-3

C32H33FN4O5

572.63

O=C1C=2C(CN1[C@@H]3C(=O)NC(=O)CC3)=CC(O[C@@H]4CN(CC5=CC6=C(C(F)=C5)N=C(C=C6)C7CCOCC7)CC4)=CC2

-20°C

Ice Packs

Small Compound