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BMS202 hydrochloride (1675203-84-5 (free base) ) - CAS 2089334-95-0

BMS202 hydrochloride (1675203-84-5 (free base) ) - CAS 2089334-95-0

MF-0012213-01

$45.13 USD
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Product Details

  • Bioactivity

    BMS202 hydrochloride (1675203-84-5 (free base) ) (PD-1/PD-L1 inhibitor 2 hydrochloride) is a small-molecule PD-1/PD-L1 interaction inhibitor (IC50: 18 nM) . Biophysical studies demonstrate that BMS202 binds directly to PD-L1. Binding of BMS202 promotes PD-L1 dimerisation and blocks the PD-L1/ PD1 interaction.

  • Target

    Apoptosis, PD-1/PD-L1

  • Related Pathways

    Cell Cycle/Checkpoint, Apoptosis, Immunology/Inflammation

  • CAS Number

    2089334-95-0

  • Purity

    0.9947

  • Molecular Formula

    C25H30ClN3O3

  • Molecular Weight

    455.97

  • SMILES

    Cl.COc1nc(OCc2cccc(c2C)-c2ccccc2)ccc1CNCCNC(C)=O

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound