BMT-090605 - CAS 1551403-51-0

BMT-090605 is a potent, selective AAK1 inhibitor with an IC50 of 0.6 nM, and inhibits BMP-2-inducible protein kinase (BIKE) and Cyclin G-associated kinase (GAK) with IC50s of 45 and 60 nM, respectively[1]. BMT-090605 also exhibits antinociceptive activity.

Serine/threonin kinase, AAK1 (AP2 associated kinase 1), Others

Others, Cell Cycle/Checkpoint, Metabolism, Neuroscience

1551352

C21H24N4O2

364.44

CN1C=2C(C=3C(C1=O)=C(C)N=CC3)=CC(C#N)=C(OC[C@H](CC(C)C)N)C2

-20°C

Ice Packs

Small Compound